Basic Information
| LncRNA/CircRNA Name | circ_0087378 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qRT-PCR |
| Sample | BC tissues, BC cell lines ZR-75-30, BCap37, BT474, MCF-7, MDA-MB-231, Hs 578T,MDA-MB-436, BT549 and human mammary gland epithelial cell line HBL100 |
| Expression Pattern | down-regulated |
| Function Description | hsa_circ_0087378 was validated to be downregulated in ER-positive BC and the hsa circ 0087378-miR1260b-SFRP1 axis was proposed to be a key regulatory pathway |
| Pubmed ID | 30417652 |
| Year | 2018 |
| Title | Identification and integrated analysis of key differentially expressed circular RNAs in ER-positive subtype breast cancer |
External Links
| Links for circ_0087378 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |