Basic Information
| LncRNA/CircRNA Name | circ_0000467 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qRT-PCR, Cell proliferation, migration, and invasion assay, Cell apoptosis assays |
| Sample | gastric cancer tissue, GC cell lines, namely, HGC??7, MGC??03, AGS, NUGC??, and GES?? |
| Expression Pattern | up-regulated |
| Function Description | Hsa_circ_0000467 was significantly upregulated in GC tissue compared to adjacent nontumor tissue (n = 51, P < 0.05). in vitro experiments demonstrated that knockdown of hsa_circ_0000467 markedly inhibited the proliferation, migration, and invasion of GC cells. Moreover, hsa_circ_0000467 silencing increased tumor apopto sis in vitro. |
| Pubmed ID | 30461077 |
| Year | 2018 |
| Title | Hsa_circ_0000467 promotes cancer progression and serves as a diagnostic and prognostic biomarker for gastric cancer |
External Links
| Links for circ_0000467 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |