Basic Information
| LncRNA/CircRNA Name | circTTC17 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qRT??CR, Colony Formation Experiment and CCK?? Assay, Wound Healing Assay |
| Sample | ESCC plasmas, ESCC tissues, cell lines HET-1A, KYSE410, TE10, TE12, KYSE70, KYSE180, KYSE450, KYSE30 |
| Expression Pattern | up-regulated |
| Function Description | The expression level of circ-TTC17 was found to be signifcantly higher in ESCC cells, plasma, and tissues compared with normal cases. In vitro experiments indicated that circ-TTC17 promoted proliferation and migration of ESCC cells. Bioinformatics predictions showed that circ-TTC17 might regulate progress of ESCC by acting as a sponge for microRNAs (miRNAs). |
| Pubmed ID | 30519852 |
| Year | 2018 |
| Title | Circ??TC17 Promotes Proliferation and Migration of Esophageal Squamous Cell Carcinoma |
External Links
| Links for circTTC17 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |