Basic Information
| LncRNA/CircRNA Name | circ_0055625 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qRT??CR, Dual??uciferase reporter assay, Cell proliferation assay, Migration and invasion assay |
| Sample | Colon cancer tissues, cell lines FHC, HT29, SW116, SW480, LOVO, HCT116, LS-174-T |
| Expression Pattern | up-regulated |
| Function Description | hsa_circ_0055625 (circ_0055625) was confirmed to be significantly upregulated in colon cancer tissues. Further analysis demonstrated that circ_0055625 might get involved in the pathogenesis of colon cancer by functioning as miRNA sponges and performed bioinformatics analysis of the predicted circ_0055625/miR 106b 5p (miR 106b)/ITGB8 network. Moreover, we found that circ_0055625 expression was associated with pathological TNM stage and metastasis. |
| Pubmed ID | 30520100 |
| Year | 2018 |
| Title | Has_circ_0055625 from circRNA profile increases colon cancer cell growth by sponging miR??06b??p |
External Links
| Links for circ_0055625 | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |