Basic Information
| LncRNA/CircRNA Name | circMTO1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, western blot |
| Sample | CRC tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | RT-PCR showed that circMTO1 expression was significantly decreased in CRC tissues and cell lines compared with adjacent non-tumor tissues and human normal colon epithelial cell line (FHC), respectively. |
| Pubmed ID | 30556859 |
| Year | 2018 |
| Title | CircMTO1 inhibits cell proliferation and invasion by regulating Wnt/?-catenin signaling pathway in colorectal cancer. |
External Links
| Links for circMTO1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |