Basic Information
| LncRNA/CircRNA Name | circNF1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | RNA-seq, luciferase reporter assay |
| Sample | GC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | we focused on one novel circRNA, circNF1, which was upregulated in GC tissues and cell lines. Loss-and gain-of-function studies demonstrated that circNF1 significantly promotes cell proliferation.Furthermore, luciferase reporter assays showed that circNF1 binds to miR-16, |
| Pubmed ID | 30576282 |
| Year | 2019 |
| Title | Novel circular RNA circNF1 acts as a molecular sponge, promoting gastric cancer by absorbing miR-16. |
External Links
| Links for circNF1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |