Basic Information
| LncRNA/CircRNA Name | circ_RAD23B |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, luciferase reporter assay |
| Sample | NSCLC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | The findings demonstrated that circ-RAD23B,identified to be amplified and overexpressed in NSCLC, was associated with lymphnode invasion, lower differentiation grade and shorter overall survival (OS). |
| Pubmed ID | 30722989 |
| Year | 2019 |
| Title | Circular RNA circ-RAD23B promotes cell growth and invasion by miR-593-3p/CCND2 and miR-653-5p/TIAM1 pathways in non-small cell lung cancer. |
External Links
| Links for circ_RAD23B | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |