Basic Information
| LncRNA/CircRNA Name | circPSMC3 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, luciferase reporter assay |
| Sample | GC tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | CircPSMC3 rather than liner PSMC3 mRNA was down-regulated in GC tissues, corresponding plasmas from GC patients as well as GC cell lines compared to normal controls. |
| Pubmed ID | 30777076 |
| Year | 2019 |
| Title | CircPSMC3 suppresses the proliferation and metastasis of gastric cancer by acting as a competitive endogenous RNA through sponging miR-296-5p. |
External Links
| Links for circPSMC3 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |