Basic Information
| LncRNA/CircRNA Name | circ_000543 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | qPCR |
| Sample | NPC tissues,cell line |
| Expression Pattern | up-regulated |
| Function Description | We found that circRNA_000543 expression was upregulated in NPC tissues compared adjacent tissues, and was higher in radioresistant samples than in radiosensitive NPC samples. |
| Pubmed ID | 30928094 |
| Year | 2019 |
| Title | CircRNA_000543 knockdown sensitizes nasopharyngeal carcinoma to irradiation by targeting miR-9/platelet-derived growth factor receptor B axis. |
External Links
| Links for circ_000543 | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |