Basic Information
| LncRNA/CircRNA Name | circMTO1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | qPCR, luciferase reporter assay, western blot |
| Sample | LUAD tissues,cell lines(A549, SPC-A1, HCC827, NCI-H1299, NCI-H23) |
| Expression Pattern | down-regulated |
| Function Description | we found that circ-MTO1 was also frequently decreased in LUAD cells and tissues, |
| Pubmed ID | 30975029 |
| Year | 2019 |
| Title | A regulatory circuit of circ-MTO1/miR-17/QKI-5 inhibits the proliferation of lung adenocarcinoma. |
External Links
| Links for circMTO1 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |