Basic Information
| LncRNA/CircRNA Name | circ_0004771 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, luciferase reporter assay, western blot |
| Sample | breast cancer tumor tissues,cell lines(T47D, MCF-7, BT549, Hs-578T, MDA-MB-231) |
| Expression Pattern | up-regulated |
| Function Description | hsa_circ_0004771 and Zinc finger E-box binding homeobox 2 (ZEB2) expression levels were up-regulated and positively correlated in breast cancer tumor tissues. |
| Pubmed ID | 30979827 |
| Year | 2019 |
| Title | Silencing of hsa_circ_0004771 inhibits proliferation and induces apoptosis in breast cancer through activation of miR-653 by targeting ZEB2 signaling pathway. |
External Links
| Links for circ_0004771 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |