Basic Information
| LncRNA/CircRNA Name | circ_0142527 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | NA | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qRT-PCR , RNA-seq |
| Sample | CRC tissues and paired adjacent normal tissues? |
| Expression Pattern | down-regulated |
| Function Description | Hsa_circ_0142527 and KLF4 mRNA were significantly lower expressed in CRC tissues in both training and confirm groups and have high positive correlation. We further found that the expression levels of hsa_circ_0142527 were significantly associated with age, differentiation , invasion , distal metastasis, TNM stage, and carcinoembryonic antigen. |
| Pubmed ID | 31169949 |
| Year | 2019 |
| Title | Expression profiles of circular RNAs in human colorectal cancer based on RNA deep sequencing |
External Links
| Links for circ_0142527 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |