Basic Information
| LncRNA/CircRNA Name | circ_0024169 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | NA | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | angiosarcoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR , RNase R digestion |
| Sample | angiosarcoma and normal tissues ,human dermal microvascular endothelial cells (HDMEC) ,angiosarcoma cell line,ISO-HAS ,human cutaneous squamous cell carcinoma (SCC) cell line,A431 |
| Expression Pattern | down-regulated |
| Function Description | We found that both relative circ_0024169 levels and circ_0024169/CUL5 ratio was decreased in normal human dermal microvascular endothelial cells (HDMEC) and angiosarcoma cell line in vitro, compared to squamous cell carcinoma line. circ_0024169/ CUL5 ratio was significantly reduced in angiosarcoma and pyogenic granuloma than other tumors in vivo, which were more evident than decreased relative circ_0024169 levels. On the other hand, relative circ_0024169 levels showed mild inverse correlation with the follow-up periods (duration between the first hospital visit and the last hospital visit/the date of death) of angiosarcoma patients. |
| Pubmed ID | 31218163 |
| Year | 2019 |
| Title | A Potential Significance of circ_0024169 Down Regulation in Angiosarcoma Tissue |
External Links
| Links for circ_0024169 | GenBank HGNC NONCODE |
| Links for angiosarcoma | OMIM COSMIC |