Basic Information
| LncRNA/CircRNA Name | circ_11783 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | NA | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qRT-PCR , circRNA sequence |
| Sample | liver metastasis tissues and primary tumor tissues ,breast cancer MDA-MB-232 cells |
| Expression Pattern | down-regulated |
| Function Description | The altered expressed circRNAs were found in BCLM tissues, compared with primary tumor tissues. These circRNAs involved in metastatic related signaling pathways. Hsa_circ_21439 and hsa_circ_11783 were verified to be the most significantly up- and downregulated circRNAs in both BCLM tissues and cells. In silico circRNA/miRNA analysis revealed that has_circ_21439 and has_circ_11783 could act as 'miRNA sponge'. |
| Pubmed ID | 31293174 |
| Year | 2019 |
| Title | The Potential Targets for Metastases: A Study on Altered Circular RNA Profile in Breast Cancer Liver Metastases |
External Links
| Links for circ_11783 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |