Basic Information
| LncRNA/CircRNA Name | circ_0001776 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | NA | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | endometrial cancer |
| ICD-0-3 | NA |
| Methods | qRT-PCR , circrnas sequencing , |
| Sample | EC and adjacent non-cancerous endometrial tissues |
| Expression Pattern | down-regulated |
| Function Description | The upregulated hsa_circ_0039569 and hsa_circ_0001610 and downregulated hsa_circ_0000437, hsa_circ_0001776, and hsa_circ_0009043 were validated by qRT-PCR analysis. Using bioinformatical methods, we found that hsa_circ_0039569 has the MRE of hsa-miR-542-3p and hsa-let-7c-5p. Hsa-miR-542-3p and hsa-let-7c-5p were downregulated in the grade 3 EC validated by qRT-PCR analysis. In the clinicopathological parameters, the expression level of hsa_circ_0039572 was significantly correlated with tumor differentiation. |
| Pubmed ID | 31308756 |
| Year | 2019 |
| Title | Analysis of the Circular RNA Transcriptome in the Grade 6 Endometrial Cancer |
External Links
| Links for circ_0001776 | GenBank HGNC NONCODE |
| Links for endometrial cancer | OMIM COSMIC |