Basic Information
| LncRNA/CircRNA Name | circ_0067582 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | NA | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qRT-PCR , immunohistochemical analysis |
| Sample | GC tissues and their adjacent non-tumorous tissues |
| Expression Pattern | down-regulated |
| Function Description | Compared with healthy control tissues, both hsa_circ_0067582 and hsa_circ_0005758 were significantly decreased in GC tissues.Besides, hsa_circ_0067582 expression was associated with GC patients' tissue CEA level and stages; and hsa_circ_0005758 expression was relevant to tissue CEA level and perineural invasion.The area under the ROC curve (AUC) of hsa_circ_0067582 was up to 0.671. The cutoff value was set at 10.61, with which the sensitivity and specificity were 55.2% and 75.1%, respectively. |
| Pubmed ID | 31328820 |
| Year | 2019 |
| Title | Clinical Significances of hsa_circ_0067582 and hsa_circ_0005758 in Gastric Cancer Tissues |
External Links
| Links for circ_0067582 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |