Basic Information
| LncRNA/CircRNA Name | circ_101505 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | liver cancer tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | We identified a novel circRNA circRNA_101505 that was decreased in cisplatin-resistant HCC tissues and cell lines, and associated with a poor survival outcome. Gain-of-function investigations showed that overexpression of circRNA_101505 suppressed cancer cell growth in vivo and in vitro, and enhanced cisplatin toxicity in HCC cells. |
| Pubmed ID | 31372241 |
| Year | 2019 |
| Title | CircRNA_101505 Sensitizes Hepatocellular Carcinoma Cells to Cisplatin by Sponging miR-103 and Promotes Oxidored-Nitro Domain-Containing Protein 1 Expression |
External Links
| Links for circ_101505 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |