Basic Information
| LncRNA/CircRNA Name | circMYLK |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | liver cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | CircMYLK was highly expressed in HCC tissues and cell lines, which was associated with poor prognosis in HCC patients. In addition, knockdown of circMYLK remarkably inhibited the proliferation, invasion, and migration of Huh7 and Hep3B cells. |
| Pubmed ID | 31413665 |
| Year | 2019 |
| Title | Circular RNA MYLK Promotes Hepatocellular Carcinoma Progression by Increasing Rab23 Expression by Sponging miR-362-3p |
External Links
| Links for circMYLK | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |