Basic Information
| LncRNA/CircRNA Name | circGFRA1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, luciferase reporter and RNA immunoprecipitation (RIP) assay |
| Sample | ovarian cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | qRT-PCR showed that circGFRA1 was overexpressed in ovarian cancer tissues. Inhibition of circGFRA1 suppressed cell proliferation and invasion, but induced cell apoptosis in ovarian cancer. |
| Pubmed ID | 31417634 |
| Year | 2019 |
| Title | circGFRA1 Promotes Ovarian Cancer Progression By Sponging miR-449a |
External Links
| Links for circGFRA1 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |