Basic Information
LncRNA/CircRNA Name | circCPA4 |
Synonyms | circ_0082374 |
Region | |
Ensemble | |
Refseq |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | glioma |
ICD-0-3 | NA |
Methods | qPCR |
Sample | glioma tissues and cell lines |
Expression Pattern | up-regulated |
Function Description | We found that circCPA4 (hsa_circ_0082374) up-regulated the most in glioma tissues and high levels of circCPA4 were positively related to poor outcome of glioma. And knockdown of circCPA4 suppresses cell proliferation and metastasis in glioma. Moreover, circCPA4 interacts with let-7 and serves as a sponge for let-7. |
Pubmed ID | 31424161 |
Year | 2019 |
Title | circCPA4 Acts as a Prognostic Factor and Regulates the Proliferation and Metastasis of Glioma |
External Links
Links for circCPA4 | GenBank HGNC NONCODE |
Links for glioma | OMIM COSMIC |