Basic Information
LncRNA/CircRNA Name | circMYLK |
Synonyms | |
Region | |
Ensemble | |
Refseq |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | laryngeal squamous cell carcinoma |
ICD-0-3 | NA |
Methods | qPCR |
Sample | laryngeal squamous cell carcinoma tissues and cell lines |
Expression Pattern | up-regulated |
Function Description | We found that circMYLK was highly expressed in LSCC tissues and cell lines. circMYLK overexpression promoted LSCC cell proliferation and G1/S cell cycle transition; whereas circMYLK knockdown had the contrary effects. |
Pubmed ID | 31427478 |
Year | 2019 |
Title | Circular RNA MYLK Serves as an Oncogene to Promote Cancer Progression via microRNA-195/cyclin D1 Axis in Laryngeal Squamous Cell Carcinoma |
External Links
Links for circMYLK | GenBank HGNC NONCODE |
Links for laryngeal squamous cell carcinoma | OMIM COSMIC |