Basic Information
| LncRNA/CircRNA Name | circ_0023642 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR and luciferase assays |
| Sample | bladder cancer cell lines |
| Expression Pattern | down-regulated |
| Function Description | ER? decreased circ_0023642 levels and subsequently increased miR-490-5p expression, resulting in decreased EGFR expression to suppress BCa cell invasion. Circ_0023642 was demonstrated to directly bind to miR-490-5p. |
| Pubmed ID | 31455760 |
| Year | 2019 |
| Title | ER?-mediated Alterations in circ_0023642 and miR-490-5p Signaling Suppress Bladder Cancer Invasion |
External Links
| Links for circ_0023642 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |