Basic Information
| LncRNA/CircRNA Name | circZKSCAN1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, Biotin-coupled probe pull-down assays, FISH and luciferase reporter assays |
| Sample | bladder cancer tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | we found that circ-ZKSCAN1 was downregulated in BCa tissues and cell lines. Circ-ZKSCAN1 levels were associated with survival, tumor grade, pathological T stage and tumor recurrence. Overexpressed circ-ZKSCAN1 inhibits cell proliferation, migration, invasion and metastasis in vitro and in vivo. |
| Pubmed ID | 31481066 |
| Year | 2019 |
| Title | Circular RNA circ-ZKSCAN1 Inhibits Bladder Cancer Progression Through miR-1178-3p/p21 Axis and Acts as a Prognostic Factor of Recurrence |
External Links
| Links for circZKSCAN1 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |