Basic Information
| LncRNA/CircRNA Name | circPITX1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | glioblastoma tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Herein, circ-PITX1 was found to be upregulated in glioblastoma and could mediate glioblastoma tissues and cell lines. Functionally, downregulation of circ-PITX1 hampered cell proliferation and accelerated cell apoptosis. |
| Pubmed ID | 31493405 |
| Year | 2019 |
| Title | Circular RNA circ-PITX1 Promotes the Progression of Glioblastoma by Acting as a Competing Endogenous RNA to Regulate miR-379-5p/MAP3K2 Axis |
External Links
| Links for circPITX1 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |