Basic Information
| LncRNA/CircRNA Name | circPTPRM |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | liver cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | CircPTPRM expression was significantly upregulated in HCC tissue (p = 0.023) based on the analysis of 30 paired samples. CircPTPRM expression positively correlated with HCC recurrence and metastasis (p = 0.039). CircPTPRM silencing reduced HCC cell proliferation, migration and invasion. |
| Pubmed ID | 31494761 |
| Year | 2019 |
| Title | Circular RNA Expression and circPTPRM Promotes Proliferation and Migration in Hepatocellular Carcinoma |
External Links
| Links for circPTPRM | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |