Basic Information
| LncRNA/CircRNA Name | circ_0023404 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, CCK-8 assay, transwell migration, invasion assay and Luciferase reporter assay |
| Sample | non-small cell lung cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | The expression of hsa_circ_0023404 was upregulated in NSCLC tissues, as well as in NSCLC cell lines. High hsa_circ_0023404 expression predicted short overall survival in NSCLC. Functionally, knockdown of hsa_circ_0023404 inhibited the proliferation, migration and invasion of NSCLC cells. |
| Pubmed ID | 31496723 |
| Year | 2019 |
| Title | Circular RNA hsa_circ_0023404 Promotes Proliferation, Migration and Invasion in Non-Small Cell Lung Cancer by Regulating miR-217/ZEB1 Axis |
External Links
| Links for circ_0023404 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |