Basic Information
| LncRNA/CircRNA Name | circADD3 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | liver cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | High circ-ADD3 expression was negatively correlated with vascular invasion, intrahepatic metastasis as well as distant metastasis. Moreover, it was identified as an effective biomarker for diagnosis and prognosis of HCC. |
| Pubmed ID | 31497351 |
| Year | 2019 |
| Title | Circular RNA circ-ADD3 Inhibits Hepatocellular Carcinoma Metastasis Through Facilitating EZH2 Degradation via CDK1-mediated Ubiquitination |
External Links
| Links for circADD3 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |