Basic Information
| LncRNA/CircRNA Name | circFBXW7 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, CCK-8 |
| Sample | colorectal cancer tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | CRC samples had a significantly lower level of circ-FBXW7 compared to normal tissue. si circ-FBXW7 notably promoted the proliferation, colony formation, cell migration and invasion of CRC cell in vitro. |
| Pubmed ID | 31519156 |
| Year | 2019 |
| Title | FBXW7 Circular RNA Regulates Proliferation, Migration and Invasion of Colorectal Carcinoma Through NEK2, mTOR, and PTEN Signaling Pathways in Vitro and in Vivo |
External Links
| Links for circFBXW7 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |