Basic Information
| LncRNA/CircRNA Name | circ_0042666 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | laryngeal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | laryngeal squamous cell carcinoma tissues |
| Expression Pattern | down-regulated |
| Function Description | Low hsa_circ_0042666 expression was closely associated with advanced tumor stage, lymph-node metastasis, and poor overall survival. In vitro function assays, we showed that hsa_circ_0042666 dramatically reduced LSCC cells proliferation and invasion in vitro. |
| Pubmed ID | 31525642 |
| Year | 2019 |
| Title | Hsa_circ_0042666 Inhibits Proliferation and Invasion via Regulating miR-223/TGFBR3 Axis in Laryngeal Squamous Cell Carcinoma |
External Links
| Links for circ_0042666 | GenBank HGNC NONCODE |
| Links for laryngeal squamous cell carcinoma | OMIM COSMIC |