Basic Information
| LncRNA/CircRNA Name | circARHGAP10 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR and luciferase reporter assay |
| Sample | non-small cell lung cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Thus, the present study aims at investigating the role of circARHGAP10 in NSCLC progression, which has been observed to be significantly upregulated in both NSCLC tissues and cell lines with profile analysis. A higher expression of circARHGAP10 also leads to a poor prognosis in NSCLC patients. Silencing circARHGAP10 also suppressed proliferation and metastasis by targeting the miR-150-5p/GLUT1 axis in NSCLC |
| Pubmed ID | 31561126 |
| Year | 2019 |
| Title | Upregulated circRNA ARHGAP10 Predicts an Unfavorable Prognosis in NSCLC Through Regulation of the miR-150-5p/GLUT-1 Axis |
External Links
| Links for circARHGAP10 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |