Basic Information
LncRNA/CircRNA Name | circHIPK3 |
Synonyms | |
Region | |
Ensemble | |
Refseq |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | non small cell lung cancer |
ICD-0-3 | C34 |
Methods | qPCR, CCK-8 and cell invasion assays |
Sample | non-small cell lung cancer tissues and cell lines |
Expression Pattern | up-regulated |
Function Description | circRNA-HIPK3 was upregulated in both NSCLC tissues and cell lines. Cell counting kit-8 (CCK-8), migration and flow-cytometry assays indicated that circRNA-HIPK3 participated in the regulation of the proliferation, migration, invasion and apoptosis of NSCLC cells. |
Pubmed ID | 31597523 |
Year | 2019 |
Title | Circular RNA HIPK3 Induces Cell Proliferation and Inhibits Apoptosis in Non-Small Cell Lung Cancer Through Sponging miR-149 |
External Links
Links for circHIPK3 | GenBank HGNC NONCODE |
Links for non small cell lung cancer | OMIM COSMIC |