Basic Information
| LncRNA/CircRNA Name | circ_0070269 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | liver cancer tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | we identified a novel circRNA (hsa_circ_0070269) was significantly decreased in HCC tissues and cell lines, low hsa_circ_0070269 expression was positively associated with advanced tumor stage, lymph node metastasis, and poor overall survival. Hsa_circ_0070269 overexpression suppressed proliferation and invasion of HCC cells in vitro and reduced tumor growth in vivo. |
| Pubmed ID | 31606623 |
| Year | 2019 |
| Title | Hsa_circ_0070269 Inhibits Hepatocellular Carcinoma Progression Through Modulating miR-182/NPTX1 Axis |
External Links
| Links for circ_0070269 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |