Basic Information
| LncRNA/CircRNA Name | circPTN |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR and western blot |
| Sample | glioma cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ_PTN was overexpressed in glioma cells, and its knockdown induced cell proliferation inhibition, cell cycle arrest and apoptosis in glioma cells. |
| Pubmed ID | 31609809 |
| Year | 2019 |
| Title | Circular RNA Pleiotrophin Promotes Carcinogenesis in Glioma via Regulation of microRNA-122/SRY-box Transcription Factor 6 Axis |
External Links
| Links for circPTN | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |