Basic Information
| LncRNA/CircRNA Name | circ_0044516 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | exosome | ||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, luciferase reporter assays |
| Sample | prostate cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ_0044516 was verified to be significantly upregulated in the exosomes from prostate cancer patients and the cell lines. Further investigation demonstrated that circ_0044516 downregulation inhibited the proliferation and metastasis of prostate cancer cells. |
| Pubmed ID | 31625175 |
| Year | 2019 |
| Title | Exosome circ_0044516 Promotes Prostate Cancer Cell Proliferation and Metastasis as a Potential Biomarker |
External Links
| Links for circ_0044516 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |