Basic Information
| LncRNA/CircRNA Name | circ_0076305 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, western blot |
| Sample | non-small cell lung cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ_0076305 was upregulated in NSCLC, and more significantly elevated in DDP-resistant NSCLC tissues and cells. Further experiments discovered that circ_0076305 could regulate DDP resistance of NSCLC cells via binding to miR-296-5p. |
| Pubmed ID | 31647948 |
| Year | 2019 |
| Title | Circ_0076305 Regulates Cisplatin Resistance of Non-Small Cell Lung Cancer via Positively Modulating STAT3 by Sponging miR-296-5p |
External Links
| Links for circ_0076305 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |