Basic Information
| LncRNA/CircRNA Name | circ_0005273 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | thyroid cancer |
| ICD-0-3 | C73.9 |
| Methods | qPCR |
| Sample | thyroid cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | qRT-PCR analyses showed that circ_0005273 were upregulated in PTC tissues and cell lines. Moreover, circ_0005273 was located in the cytoplasm of PTC cells and suggested poor prognosis in PTC patients. In vivo and in vitro functional assays indicated that knockdown of circ_0005273 inhibited PTC tumor growth and progression, respectively |
| Pubmed ID | 31693489 |
| Year | 2019 |
| Title | circ_0005273 Promotes Thyroid Carcinoma Progression by SOX2 Expression |
External Links
| Links for circ_0005273 | GenBank HGNC NONCODE |
| Links for thyroid cancer | OMIM COSMIC |