Basic Information
| LncRNA/CircRNA Name | circ_0008450 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR, CCK8, flow cytometry and Luciferase reporter assay |
| Sample | liver cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | hsa_circ_0008450 was significantly increased in HCC tissues and cells. Furthermore, knockdown of hsa_circ_0008450 in HCC cells inhibited cell proliferation, invasion, and migration. |
| Pubmed ID | 31695501 |
| Year | 2019 |
| Title | Silencing Of hsa_circ_0008450 Represses Hepatocellular Carcinoma Progression Through Regulation Of microRNA-214-3p/EZH2 Axis |
External Links
| Links for circ_0008450 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |