Basic Information
| LncRNA/CircRNA Name | circHuR |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Biotin-labeled RNA pull-down, mass spectrometry, RNA immunoprecipitation, RNA electrophoretic mobility shift |
| Sample | gastric cancer tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | Circ-HuR (hsa_circ_0049027) was predominantly detected in the nucleus, and was down-regulated in gastric cancer tissues and cell lines. Ectopic expression of circ-HuR suppressed the growth, invasion, and metastasis of gastric cancer cells in vitro and in vivo. |
| Pubmed ID | 31718709 |
| Year | 2019 |
| Title | Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation |
External Links
| Links for circHuR | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |