Basic Information
| LncRNA/CircRNA Name | circENO1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | qPCR |
| Sample | lung adenocarcinoma tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ-ENO1 and its host gene ENO1 were identified to be upregulated in LUAD cells. Functionally, silencing circ-ENO1 retarded glycolysis, inhibited proliferation, migration and EMT, induced apoptosis. In vivo experiments certified that circ-ENO1 drove tumor growth and metastasis in vivo. |
| Pubmed ID | 31767835 |
| Year | 2019 |
| Title | CircRNA-ENO1 promoted glycolysis and tumor progression in lung adenocarcinoma through upregulating its host gene ENO1 |
External Links
| Links for circENO1 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |