Basic Information
| LncRNA/CircRNA Name | circ_0004136 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute myeloid leukemia |
| ICD-0-3 | NA |
| Methods | qPCR, CCK-8 and Luciferase reporter assay |
| Sample | acute myeloid leukemia plasma |
| Expression Pattern | up-regulated |
| Function Description | Circ-0004136 was found to be significantly upregulated in pediatric AML and could sponge AML-related miRNAs, including miR-29a and miR-142. |
| Pubmed ID | 31773676 |
| Year | 2019 |
| Title | Identification of non-coding RNA regulatory networks in pediatric acute myeloid leukemia reveals circ-0004136 could promote cell proliferation by sponging miR-142 |
External Links
| Links for circ_0004136 | GenBank HGNC NONCODE |
| Links for acute myeloid leukemia | OMIM COSMIC |