Basic Information
| LncRNA/CircRNA Name | circFGFR1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, CCK-8, clonal formation, wound healing, and Matrigel Transwell assays |
| Sample | non-small cell lung cancer tissues and cell liens |
| Expression Pattern | up-regulated |
| Function Description | Here, we report that circFGFR1 is upregulated in NSCLC tissues, and circFGFR1 expression is associated with deleterious clinicopathological characteristics and poor prognoses for NSCLC patients. Forced circFGFR1 expression promoted the migration, invasion, proliferation, and immune evasion of NSCLC cells. |
| Pubmed ID | 31815619 |
| Year | 2019 |
| Title | Circular RNA circFGFR1 promotes progression and anti-PD-1 resistance by sponging miR-381-3p in non-small cell lung cancer cells |
External Links
| Links for circFGFR1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |