Basic Information
| LncRNA/CircRNA Name | circMYBL2 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, CCK-8 assay, colony formation assay and transwell invasion assay |
| Sample | cervical cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | We showed that the expression of circ-MYBL2 was significantly upregulated and positively associated with advanced FIGO stage, larger tumor size, lymph node metastasis, and poor prognosis in CC patients. Function assays revealed that circ-MYBL2 inhibition suppressed CC cells' proliferation, invasion and epithelial-mesenchymal transition (EMT) processes. |
| Pubmed ID | 31819492 |
| Year | 2019 |
| Title | circ-MYBL2 Serves As A Sponge For miR-361-3p Promoting Cervical Cancer Cells Proliferation And Invasion |
External Links
| Links for circMYBL2 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |