Basic Information
| LncRNA/CircRNA Name | circASAP1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | liver cancer cell lines |
| Expression Pattern | up-regulated |
| Function Description | CircASAP1 was overexpressed in HCC cell lines with high metastatic potential and in metastatic HCCs. In vitro, circASAP1 promoted cell proliferation, colony formation, migration, and invasion, and in vivo it enhanced tumor growth and pulmonary metastasis. |
| Pubmed ID | 31838741 |
| Year | 2019 |
| Title | Circular RNA Sequencing Identifies CircASAP1 as a Key Regulator in Hepatocellular Carcinoma Metastasis |
External Links
| Links for circASAP1 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |