Basic Information
| LncRNA/CircRNA Name | circMTHFD2 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, CCK-8 and luciferase reporter assay |
| Sample | gastric cancer cell lines |
| Expression Pattern | up-regulated |
| Function Description | Compared with MGC-803/MTA resistant cells, the drug resistance of cells increased significantly in circ MTHFD2 overexpression group. |
| Pubmed ID | 31841184 |
| Year | 2019 |
| Title | Effect of circ MTHFD2 on resistance to pemetrexed in gastric cancer through regulating expression of miR-124 |
External Links
| Links for circMTHFD2 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |