Basic Information
| LncRNA/CircRNA Name | circSMO742 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, western blot, MTT assay, transwell assays and flow cytometry |
| Sample | glioma tissues |
| Expression Pattern | up-regulated |
| Function Description | CircSMO742 and SMO were highly expressed in glioma tissues, while miR-338-3p expression was reduced. CircSMO742 together with SMO could promote cells proliferation, migration and invasion while inhibit cells apoptosis, whereas miR-338-3p showed negative impacts on the cell activity. |
| Pubmed ID | 31895689 |
| Year | 2020 |
| Title | Circular RNA SMO sponges miR-338-3p to promote the growth of glioma by enhancing the expression of SMO |
External Links
| Links for circSMO742 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |