Basic Information
| LncRNA/CircRNA Name | circEPB41L5 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | luciferase reporter and RNA pull-down assays |
| Sample | glioblastoma tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | Circ-EPB41L5 was downregulated in glioblastoma tissues and cell lines compared to the normal brain tissues and cell lines. Low circ-EPB41L5 expression was correlated to the poor prognosis of glioblastoma patients, while the overexpression inhibited proliferation, clone formation, migration, and invasion abilities of glioma cells, and the suppression had counter effects. |
| Pubmed ID | 31905344 |
| Year | 2020 |
| Title | Circ-EPB41L5 regulates the host gene EPB41L5 via sponging miR-19a to repress glioblastoma tumorigenesis |
External Links
| Links for circEPB41L5 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |