Basic Information
| LncRNA/CircRNA Name | circSOX4 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | qPCR. CCK-8, colony formation, transwell and wound healing assays |
| Sample | lung adenocarcinoma tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ-SOX4 was found to be obviously upregulated in LUAD tissues and cells, and knockdown of it inhibited cell proliferation, invasion and migration in LUAD. |
| Pubmed ID | 31911754 |
| Year | 2020 |
| Title | Circ-SOX4 drives the tumorigenesis and development of lung adenocarcinoma via sponging miR-1270 and modulating PLAGL2 to activate WNT signaling pathway |
External Links
| Links for circSOX4 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |