Basic Information
| LncRNA/CircRNA Name | circ_0000370 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute myeloid leukemia |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | acute myeloid leukemia plasma and cell lines |
| Expression Pattern | up-regulated |
| Function Description | circ_0000370 was found to be significantly increased in FLT3-ITD+ AML and was demonstrated to act as an oncogenic circRNA of AML in vitro. |
| Pubmed ID | 31919040 |
| Year | 2020 |
| Title | A novel circular RNA (hsa_circ_0000370) increases cell viability and inhibits apoptosis of FLT3-ITD-positive acute myeloid leukemia cells by regulating miR-1299 and S100A7A |
External Links
| Links for circ_0000370 | GenBank HGNC NONCODE |
| Links for acute myeloid leukemia | OMIM COSMIC |