Basic Information
| LncRNA/CircRNA Name | circRHOBTB3 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Dual luciferase reporter and RNA pull-down assays |
| Sample | gastric cancer tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | The expression of circRHOBTB3 was lower in GC tissues and cell lines. Downregulation of circRHOBTB3 was significantly correlated with poor differentiation and unfavorable prognosis in patients with GC. Overexpression of circRHOBTB3 in GC cells led to decreased proliferation |
| Pubmed ID | 31928527 |
| Year | 2020 |
| Title | Circular RNA circRHOBTB3 acts as a sponge for miR-654-3p inhibiting gastric cancer growth |
External Links
| Links for circRHOBTB3 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |