Basic Information
| LncRNA/CircRNA Name | circABCB10 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, CCK-8, colony formation, TUNEL and transwell assays |
| Sample | lung cancer cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ-ABCB10 was markedly upregulated and featured with loop structure in lung cancer. Circ-ABCB10 depletion suppresses lung cancer progression and sensitizes lung cancer cells to cisplatin. |
| Pubmed ID | 31931771 |
| Year | 2020 |
| Title | Knockdown of circ-ABCB10 promotes sensitivity of lung cancer cells to cisplatin via miR-556-3p/AK4 axis |
External Links
| Links for circABCB10 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |